Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

High dose 5‐ASA vs low dose 5‐ASA

Withdrawals due to adverse events · people with surgically‐induced remission in Crohn's disease

High dose 5‐ASA showed no clear difference in withdrawal due to adverse events compared with low dose 5‐ASA (low certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid for maintenance of surgically‐induced remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 1.04 [0.15, 7.24]
1 study · 206 participants
Low

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

Withdrawals due to adverse events · people with inflammatory bowel disease

It is very uncertain whether high‐treatment‐dose vitamin D (greater than 1000 IU/day) changes withdrawals due to adverse events compared with low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day) (very low certainty).

1 finding from 1 review

Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
RR 0.89 [0.06, 13.08]
3 studies · 104 participants
Very low