Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Beclometasone vs placebo

Withdrawal (all‐cause) · participants with stable stage 2 and 3 COPD (mainly FEV1 49 ± 12% predicted), ex‐smokers (majority), smokers and non‐smokers

Beclometasone showed no clear difference in withdrawal (all‐cause) compared with placebo (low certainty).

1 finding from 1 review

Beclometasone/LABA vs LABA

Withdrawal (all‐cause) · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

Beclometasone/LABA showed no clear difference in withdrawal (all‐cause) compared with LABA (moderate certainty).

1 finding from 1 review