Fluoride varnish vs Placebo varnish, resin sealant, or standard care (oral hygiene instructions)
White spot lesion clinical score (mean values), subject level · Healthy adolescents and adults undergoing orthodontic treatment with fixed multi-bracket appliances
In a pooled analysis of two placebo-controlled trials, fluoride varnish also reduced white spot lesion clinical scores (pooled SMD -0.44, 95% CI -0.64 to -0.24); this secondary outcome was not separately GRADE-rated.
1 finding from 1 review
- Prevention of white spot lesions with fluoride varnish during orthodontic treatment with fixed appliances: a… 2023 All outcomesAt debonding · Orthodontic care (fixed multi-bracket appliance treatment)SMD -0.44 [-0.64, -0.24]2 studies · 258 participantsGRADE not reported