Findings

What do systematic reviews say?

11 questions · 11 findings · 5 reviews · Emergency and Critical Care

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No studies found 2 · 18.2%GRADE not reported 0 · 0%Very low 4 · 36.4%Low 2 · 18.2%Moderate 2 · 18.2%High 1 · 9.1%

HALOPERIDOL vs placebo

Ventilator‐free days up to day 28 · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1439 participants
High

Surfactants vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 344 participants
Very low

N‐acetylcysteine vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Statins vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1342 participants
Moderate

Beta‐agonist vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 646 participants
Very low

Corticosteroids vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 494 participants
Low

Early vs late tracheostomy

Ventilator‐free days up to day 28 · critically ill patients

1 finding from 1 review

Early versus late tracheostomy for critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 335 participants
Moderate

Enteral vs enteral and parenteral nutrition

Ventilator‐free days up to day 28 · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral versus parenteral nutrition and enteral versus a combination of enteral and parenteral nutrition for adults in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enteral vs parenteral nutrition

Ventilator‐free days up to day 28 · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

1 finding from 1 review

Enteral versus parenteral nutrition and enteral versus a combination of enteral and parenteral nutrition for adults in… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2388 participants
Very low

Physical and cognitive therapy vs usual care

Ventilator‐free days (within the first 30 days) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 65 participants
Very low

High levels of PEEP vs low levels of PEEP

Ventilator‐free days up to day 28 · patients with ALI and ARDS

1 finding from 1 review

High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1654 participants
Low