What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral medicine and oral cancer

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Daily chewing gum for 2 weeks or longer vs No gum chewing or control

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

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1 finding from 1 review

The effect of gum chewing on xerostomia and salivary flow rate in elderly and medically compromised subjects: a… 2023 All outcomes
2 to 12 weeks · Meta-regression slope for change in standardized salivary flow rate per additional week of chewing · Meta-regression by chewing duration
SMD per week 0.06
6 studies · 291 participants
GRADE not reported

Gum chewing (sugar-free) vs No chewing gum

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

In elderly and medically compromised people with xerostomia, chewing sugar-free gum daily for two or more weeks produces a small but statistically significant increase in unstimulated whole salivary flow rate versus no gum (SMD 0.44, 95% CI 0.22 to 0.66); certainty of evidence was not formally graded.

1 finding from 1 review

The effect of gum chewing on xerostomia and salivary flow rate in elderly and medically compromised subjects: a… 2023 All outcomes
Gum chewed daily for >=2 weeks (2 to 12 weeks; multiple time points for Kim and Ozen) · Haemodialysis units, elderly / geriatric care, cancer and palliative care, and xerostomia / hyposalivation clinics (studies from multiple countries)
SMD 0.44 [0.22, 0.66]
6 studies · 291 participants
GRADE not reported