Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 1 · 33.3%

Combination vs single‐agent chemotherapy

Tumour response · people with advanced gastric cancer

Combination leads to higher tumour response compared with single‐agent chemotherapy (high certainty).

1 finding from 1 review

Chemotherapy for advanced gastric cancer 2017 · Cochrane Headline outcomes only
OR 2.3 [1.94, 2.72]
18 studies · 2833 participants
High

5‐FU/cisplatin/anthracycline combinations vs 5‐FU/cisplatin combinations (without anthracyclines)

Tumour response · people with advanced gastric cancer

5‐FU/cisplatin/anthracycline combinations may leads to higher tumour response compared with 5‐FU/cisplatin combinations (without anthracyclines) (low certainty).

1 finding from 1 review

Chemotherapy for advanced gastric cancer 2017 · Cochrane Headline outcomes only
OR 2.86 [1.14, 7.16]
1 study · 78 participants
Low

Taxane‐platinum‐fluoropyrimidine combinations vs taxane‐platinum (without fluoropyrimidine)

Tumour response · people with advanced gastric cancer

Taxane‐platinum‐fluoropyrimidine combinations may leads to higher tumour response compared with taxane‐platinum (without fluoropyrimidine) (low certainty).

1 finding from 1 review

Chemotherapy for advanced gastric cancer 2017 · Cochrane Headline outcomes only
OR 2.08 [1.37, 3.15]
3 studies · 482 participants
Low