Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Childhood Cancer

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Amifostine vs no otoprotective intervention

Tumour response · children with cancer treated with platinum‐based therapy

The review found no eligible studies for this question.

1 finding from 1 review

Medical interventions for the prevention of platinum‐induced hearing loss in children with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amifostine vs no otoprotective intervention

Tumour response with intra‐arterial platinum (good and partial remission) · children with cancer treated with platinum‐based therapy

Amifostine showed no clear difference in tumour response with intra‐arterial platinum (good and partial… compared with no otoprotective intervention (low certainty).

1 finding from 1 review

Medical interventions for the prevention of platinum‐induced hearing loss in children with cancer 2019 · Cochrane Headline outcomes only
RR 1.6 [0.97, 2.63]
1 study · 27 participants
Low