Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Treatment failure To discharge · newborn infants with opioid withdrawal

It is very uncertain whether morphine changes treatment failure To discharge compared with buprenorphine (very low certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 0.79 [0.36, 1.74]
3 studies · 113 participants
Very low

Treatment failure To discharge · newborn infants with opioid withdrawal

Morphine showed no clear difference in treatment failure To discharge compared with methadone (low certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 1.59 [0.95, 2.67]
2 studies · 147 participants
Low