What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Hypertension

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%

First‐line thiazides vs ACE inhibitor

Cardiovascular events · patients with hypertension

First‐line thiazides showed no clear difference in total cardiovascular events Duration: 2.6 to 5 years compared with first‐line ACE inhibitors (low certainty).

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
RR 0.97 [0.92, 1.02]
3 studies · 30900 participants
Low