NSAIDs vs glucocorticoids
Total adverse events · acute gout
NSAIDs probably leads to higher total adverse events compared with glucocorticoids (moderate certainty).
1 finding from 1 review
- RR 1.62 [1.03, 2.55]Studies not reportedModerate
Findings
What do systematic reviews say?
4 questions · 4 findings · 2 reviews · Headline outcomes only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%
NSAIDs vs placebo
Total adverse events · acute gout
NSAIDs showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 0.2 [0.01, 3.85]Studies not reportedLow
Non‐selective NSAIDs vs selective cyclo‐oxygenase‐2 inhibitors
Total adverse events · acute gout
Non‐selective NSAIDs probably leads to higher total adverse events compared with selective cyclo‐oxygenase‐2 inhibitors (moderate certainty).
1 finding from 1 review
- RR 1.94 [1.36, 2.78]Studies not reportedModerate
Low‐dose colchicine vs NSAIDs
Number of participants reporting an adverse event · acute gout
Low‐dose colchicine showed no clear difference in total number of participants reporting adverse events compared with NSAIDs (low certainty).
1 finding from 1 review
- RR 1.07 [0.88, 1.29]1 study · 399 participantsLow