Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Epilepsy

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Topiramate vs carbamazepine

Time to treatment failure (any reason related to treatment) Subgroup: focal onset seizures Range of · adults and children with newly onset partial or generalised epilepsy

Topiramate probably leads to higher time to treatment failure (any reason related to treatment)Subgroup:… compared with carbamazepine (moderate certainty).

1 finding from 1 review

Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review 2019 · Cochrane Headline outcomes only
HR 1.21 [1.01, 1.46]
2 studies · 937 participants
Moderate