Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Epilepsy

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Sodium valproate vs phenytoin monotherapy

Remission · adults and children with newly‐onset focal onset or generalised tonic‐clonic seizures

Sodium valproate showed no clear difference in time to achieve 12‐month remission (seizure‐free period) All… compared with phenytoin monotherapy (moderate certainty).

1 finding from 1 review

Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review 2018 · Cochrane Headline outcomes only
HR 1.02 [0.81, 1.28]
4 studies · 514 participants
Moderate

Carbamazepine vs phenobarbitone

Remission · adults and children with newly onset partial or generalised epilepsy

Carbamazepine showed no clear difference in time to achieve 12‐month remission (seizure‐free period) All… compared with phenobarbitone (low certainty).

1 finding from 1 review

Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review 2018 · Cochrane Headline outcomes only
HR 1.09 [0.84, 1.4]
4 studies · 683 participants
Low