Findings

What do systematic reviews say?

5 questions · 5 findings · 3 reviews

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No studies found 2 · 40%GRADE not reported 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

Unfractionated heparin vs low molecular weight heparin

Thrombocytopenia · CRRT

It is very uncertain whether unfractionated heparin changes thrombocytopenia compared with low molecular weight heparin (very low certainty).

1 finding from 1 review

Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
RR 0.57 [0.2, 1.63]
2 studies · 124 participants
Very low

Unfractionated heparin vs no pharmacological anticoagulation

Thrombocytopenia · CRRT

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low molecular weight heparin vs unfractionated heparin

Thrombocytopenia · patients with cancer with venous thromboembolism

The review found no eligible studies for this question.

1 finding from 1 review

Anticoagulation for the initial treatment of venous thromboembolism in people with cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

Unfractionated heparin versus low molecular weight heparins for avoiding heparin‐induced thrombocytopenia in… 2017 · Cochrane Headline outcomes only
RR 0.23 [0.07, 0.73]
3 studies · 1398 participants
Low

Citrate vs unfractionated heparin

Thrombocytopenia · CRRT

Citrate showed no clear difference in thrombocytopenia compared with unfractionated heparin (low certainty).

1 finding from 1 review

Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
RR 0.39 [0.14, 1.03]
3 studies · 412 participants
Low