Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Switch to a specific antipsychotic vs switch to a different specific antipsychotic

Tardive dyskinesia: No clinically important improvement · patients with antipsychotic‐induced tardive dyskinesia

1 finding from 1 review

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 140 participants
Very low

Reduced dose of antipsychotics vs antipsychotic maintenance

Tardive dyskinesia: No clinically important improvement · female and male 42 (mean) years old patients with schizophrenia or schizoaffective disorder and antipsychotic‐induced tardive dyskinesia

It is very uncertain whether reduced dose of antipsychotics changes tardive dyskinesia: no clinically important improvement compared with antipsychotic maintenance (very low certainty).

1 finding from 1 review

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 0.42 [0.17, 1.04]
2 studies · 17 participants
Very low

Switch to another antipsychotic vs antipsychotic cessation

Tardive dyskinesia: No clinically important improvement · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

Switch to another antipsychotic may leads to lower tardive dyskinesia: no clinically important improvement compared with antipsychotic cessation (low certainty).

1 finding from 1 review

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 0.45 [0.23, 0.89]
1 study · 42 participants
Low