Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Intervention not reported

TMZ (3 RCTs, 538 participants) · elderly people with newly diagnosed glioblastoma Interventions: chemoradiotherapy (CRT); chemoradiotherapy plus bevacizumab (BEV_CRT);…

The intervention showed no clear difference in TMZ (3 RCTs, 538 participants) (low certainty).

1 finding from 1 review

Treatment of newly diagnosed glioblastoma in the elderly: a network meta‐analysis 2020 · Cochrane Headline outcomes only
HR 0.95 [0.71, 1.26]
3 studies · 538 participants
Low

Intervention not reported

TMZ (3 RCTs, 538 participants) · elderly people with newly diagnosed glioblastoma Interventions: radiotherapy with 40 Gy in 15 fractions (RT 40); chemoradiotherapy (CRT);…

It is very uncertain whether the intervention changes TMZ (3 RCTs, 538 participants) (very low certainty).

1 finding from 1 review

Treatment of newly diagnosed glioblastoma in the elderly: a network meta‐analysis 2020 · Cochrane Headline outcomes only
HR 0.89 [0.71, 1.11]
3 studies · 538 participants
Very low

Intervention not reported

TMZ (3 RCTs, 538 participants) · elderly people with newly diagnosed glioblastoma Interventions: radiotherapy with 40 Gy in 15 fractions (RT40); radiotherapy with 60 Gy in…

The intervention may leads to lower TMZ (3 RCTs, 538 participants) (low certainty).

1 finding from 1 review

Treatment of newly diagnosed glioblastoma in the elderly: a network meta‐analysis 2020 · Cochrane Headline outcomes only
HR 0.42 [0.25, 0.71]
3 studies · 538 participants
Low