Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Postnatal prophylaxis: LMWH vs no treatment/placebo

Symptomatic DVT · women at increased risk of VTE in the early postpartum period

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Very low

Heparin prophylaxis vs no treatment/placebo

Symptomatic DVT · pregnant women at increased risk of VTE during pregnancy and the early postnatal period

It is very uncertain whether antenatal (± postnatal) prophylaxis: heparin (LMWH or UFH) changes symptomatic DVT ( compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
RR 0.33 [0.04, 3.1]
4 studies · 227 participants
Very low

Peripartum/postnatal prophylaxis: UFH vs no treatment

Symptomatic DVT · women with varicose veins before birth, having a caesarean (elective or emergency) or vaginal birth

It is very uncertain whether peripartum/postnatal prophylaxis: UFH changes symptomatic DVT ( compared with no treatment (very low certainty).

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
RR 0.27 [0.03, 2.55]
1 study · 210 participants
Very low

Peripartum/postnatal prophylaxis (caesarean): heparin (LMWH or UFH) vs no treatment/placebo

Symptomatic DVT · women giving birth by elective or emergency caesarean (elective only (1 trial), emergency or elective (4 trials))

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1140 participants
Very low