What do systematic reviews say?

Citrate vs unfractionated heparin

Citrate probably leads to higher successful prevention of clotting compared with unfractionated heparin (moderate certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 1.44 [1.1, 1.87]
  3 studies · 88 participants
  Moderate