Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 50%High 3 · 50%

Stroke · Post‐menopausal women without prior cardiovascular disease

Hormone therapy leads to higher stroke compared with placebo (high certainty).

1 finding from 1 review

Hormone therapy for preventing cardiovascular disease in post‐menopausal women 2015 · Cochrane Headline outcomes only
RR 1.32 [1.12, 1.56]
4 studies · 28719 participants
High

Stroke · Post‐menopausal women with pre‐exisiting cardiovascular disease

Hormone therapy showed no clear difference in stroke compared with placebo (moderate certainty).

1 finding from 1 review

Hormone therapy for preventing cardiovascular disease in post‐menopausal women 2015 · Cochrane Headline outcomes only
RR 1.09 [0.89, 1.33]
5 studies · 5172 participants
Moderate

Stroke · relatively healthy postmenopausal women

Oestrogen‐only hormone therapy (HT) probably leads to higher stroke compared with placebo (moderate certainty).

1 finding from 1 review

Long‐term hormone therapy for perimenopausal and postmenopausal women 2017 · Cochrane Headline outcomes only
RR 1.33 [1.06, 1.67]
1 study · 10739 participants
Moderate

Stroke · relatively healthy postmenopausal women

Combined continuous hormone therapy (HT) probably leads to higher stroke compared with placebo (moderate certainty).

1 finding from 1 review

Long‐term hormone therapy for perimenopausal and postmenopausal women 2017 · Cochrane Headline outcomes only
RR 146 [1.02, 2.09]
2 studies · 17585 participants
Moderate

Stroke · Post‐menopausal women

The intervention showed no clear difference in stroke (high certainty).

1 finding from 1 review

Hormone therapy for preventing cardiovascular disease in post‐menopausal women 2015 · Cochrane Headline outcomes only
RR 1.37 [0.8, 2.34]
3 studies · 8143 participants
High

Stroke · Post‐menopausal women

The intervention leads to higher stroke (high certainty).

1 finding from 1 review

Hormone therapy for preventing cardiovascular disease in post‐menopausal women 2015 · Cochrane Headline outcomes only
RR 1.21 [1.06, 1.38]
8 studies · 22722 participants
High