Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Serlopitant 5 mg vs placebo

Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 5 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 0.49 [0.24, 1.01]
1 study · 128 participants
Very low

Serlopitant 1 mg vs placebo

Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 1 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 0.38 [0.17, 0.84]
1 study · 128 participants
Very low

Serlopitant 0.25 mg vs placebo

Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 0.25 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 0.6 [0.31, 1.17]
1 study · 127 participants
Very low