Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 100%

Severe adverse effects · people with metastatic CRC

Irinotecan + targeted therapy leads to higher severe adverse effects compared with irinotecan (high certainty).

1 finding from 1 review

Second‐line systemic therapy for metastatic colorectal cancer 2017 · Cochrane Headline outcomes only
RR 1.44 [1.31, 1.59]
2 studies · 1704 participants
High