Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Preoperative blood transfusion vs no transfusion

Serious infection · people with SCD

It is very uncertain whether preoperative blood transfusion changes serious infection compared with no transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
OR 1.29 [0.29, 5.71]
2 studies · 434 participants
Very low

Aggressive vs conservative blood transfusion

Serious infection ‐ cholecystectomy · people with SCD

It is very uncertain whether aggressive changes serious infection ‐ cholecystectomy compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.75 [0.59, 5.18]
1 study · 230 participants
Very low