What do systematic reviews say?

Summary of findings: pioglitazone monotherapy vs intensive behaviour‐changing intervention

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 103 participants
  Low

Summary of findings: pioglitazone monotherapy vs placebo

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  3 [0.32, 28.22]
  2 studies · 187 participants
  Very low

Summary of findings: pioglitazone monotherapy vs no intervention

Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  RR 0.71 [0.38, 1.32]
  7 studies · 1211 participants
  Low

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

The review found no eligible studies for this question.

• Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found