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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Gut

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Chemotherapy vs placebo, best supportive care (BSC) or no treatment

Serious adverse events · advanced gastric and oesophago‐gastric junction adenocarcinoma

Chemotherapy probably leads to higher serious adverse events compared with placebo, best supportive care (BSC) or no treatment (moderate certainty).

1 finding from 1 review

Biological therapy vs placebo, best supportive care (BSC) or no treatment

Serious adverse events · advanced gastric and oesophago‐gastric junction adenocarcinoma

Biological therapy showed no clear difference in serious adverse events compared with placebo, best supportive care (BSC) or no treatment (low certainty).

1 finding from 1 review