Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews · Infectious Diseases

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No studies found 4 · 50%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%

Fluoroquinolones vs macrolides

Serious adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fluoroquinolones vs beta‐lactams

Serious adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes serious adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 10.9 [0.61, 194.82]
1 study · 221 participants
Very low

Ceftriaxone vs fluoroquinolones

Serious adverse events · adults and children with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cefixime vs fluoroquinolones

Serious adverse events · adults and children with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fluoroquinolone substitution for ethambutol in a standard six month regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes serious adverse events compared with standard regimen (very low certainty).

1 finding from 1 review

Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
RR 0.93 [0.53, 1.62]
3 studies · 723 participants
Very low

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in serious adverse events compared with standard regimen (low certainty).

1 finding from 1 review

Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
RR 1.1 [0.43, 2.8]
1 study · 433 participants
Low

Fluoroquinolone plus standard regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

It is very uncertain whether fluoroquinolone plus standard regimen changes serious adverse events compared with standard regimen alone (very low certainty).

1 finding from 1 review

Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
RR 0.85 [0.4, 1.78]
1 study · 174 participants
Very low

Cotrimoxazole vs fluoroquinolones

Serious adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found