What do systematic reviews say?

Fibrinolytics vs placebo

Fibrinolytics showed no clear difference in serious adverse events compared with placebo (low certainty).

• Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
  OR 1.28 [0.36, 4.57]
  9 studies · 935 participants
  Low