Findings

What do systematic reviews say?

182 questions · 183 findings · 59 reviews

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No studies found 71 · 38.8%GRADE not reported 11 · 6%Very low 57 · 31.1%Low 24 · 13.1%Moderate 15 · 8.2%High 5 · 2.7%

Intervention not reported

Serious adverse events ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Lifestyle interventions for acute gout 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lamivudine vs no intervention

Serious adverse events (6 to 12 months) · people with acute HBV infection

1 finding from 1 review

Pharmacological interventions for acute hepatitis B infection 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 250 participants
Very low

Intervention not reported

Adverse events (serious adverse events) · children (aged 6 to 11 years) being overweight or obese

The intervention showed no clear difference in adverse events (serious adverse events) (low certainty).

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
RR 0.57 [0.17, 1.93]
31 studies · 4096 participants
Low

Thiazolidinediones vs no intervention

Serious adverse events (number of events) · people with non‐alcohol‐related fatty liver disease (NAFLD)

It is very uncertain whether thiazolidinediones changes serious adverse events (number of events) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for non‐alcohol related fatty liver disease (NAFLD) 2017 · Cochrane Headline outcomes only
rate ratio 0.25 [0.06, 1.05]
3 studies · 357 participants
Very low

Antioxidants vs no intervention

Serious adverse events (number of events) · people with non‐alcohol‐related fatty liver disease (NAFLD)

It is very uncertain whether antioxidants changes serious adverse events (number of events) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for non‐alcohol related fatty liver disease (NAFLD) 2017 · Cochrane Headline outcomes only
rate ratio 0.89 [0.36, 2.19]
2 studies · 254 participants
Very low

Bile acids vs no intervention

Serious adverse events (number of events) · people with non‐alcohol‐related fatty liver disease (NAFLD)

It is very uncertain whether bile acids changes serious adverse events (number of events) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for non‐alcohol related fatty liver disease (NAFLD) 2017 · Cochrane Headline outcomes only
Rate ratio 1.01 [0.66, 1.54]
3 studies · 404 participants
Very low

Colchicine vs no intervention

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ciclosporin vs no intervention

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

D‐Penicillamine vs no intervention

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Colchicine plus ursodeoxycholic acid (UDCA) vs UDCA

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Methotrexate plus ursodeoxycholic acid (UDCA) vs UDCA

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ursodeoxycholic acid vs no intervention

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Azathioprine vs no intervention

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs control

Non‐serious adverse events (range 2–10 months) · adult patients after liver transplantation.

1 finding from 1 review

Exercise interventions for adults after liver transplantation 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
GRADE not reported

Corticosteroids vs placebo compared

Serious adverse events (dichotomous data) ‐ shock · critically ill patients

Corticosteroids showed no clear difference in serious adverse events (dichotomous data) ‐ shock compared with placebo compared (high certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 0.41 [0.17, 1.01]
1 study · 180 participants
High

Shock wave lithotripsy vs ureteroscopy with holmium laser or pneumatic lithotripsy

Serious adverse events or complications of treatment

It is very uncertain whether shock wave lithotripsy changes serious adverse events or complications of treatment compared with ureteroscopy with holmium laser or pneumatic lithotripsy (very low certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 0.56 [0.12, 2.58]
3 studies · 153 participants
Very low

Shock wave lithotripsy vs mini‐percutaneous nephrolithotripsy

Serious adverse events or complications of treatment

Shock wave lithotripsy may leads to lower serious adverse events or complications of treatment compared with mini‐percutaneous nephrolithotripsy (low certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 0.13 [0.02, 0.98]
1 study · 212 participants
Low

Shock wave lithotripsy vs dissolution therapy

Serious adverse events or complications of treatment

It is very uncertain whether shock wave lithotripsy changes serious adverse events or complications of treatment compared with dissolution therapy (very low certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 1.23 [0.08, 19.05]
1 study · 87 participants
Very low

Alpha‐blockers vs placebo with/without analgesics

Serious adverse events or complications of treatment

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Very low

Slow shock wave lithotripsy vs rapid shock wave lithotripsy

Serious adverse events or complications of treatment

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low