Gastroesophageal or laryngopharyngeal reflux (GERD/LPR) vs Healthy controls
Salivary function impairment (buffering capacity, flow rate, oral pH) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR)
Reflux is associated with impaired salivary function (notably reduced buffering capacity) as a proposed pathophysiological mechanism, based on several ungraded studies.
1 finding from 1 review
- Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. 2020 All outcomesAdult patients in gastroenterology, ENT and dental clinical settingsMixed/controversial salivary findings: reduced salivary buffering capacity supported in three studies (Correa, Holbrook, Filipi) with low oral pH and reduced flow as additional factors in GERD patients, but Meurman and Schroeder found no significant salivary abnormalities; no pooled estimate.6 studiesGRADE not reported