What do systematic reviews say?

Sugammadex (any dose) vs neostigmine (any dose)

Sugammadex (any dose) showed no clear difference in risk of serious adverse eventsb compared with neostigmine (any dose) (low certainty).

• Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults 2017 · Cochrane Headline outcomes only
  RR 0.54 [0.13, 2.25]
  10 studies · 959 participants
  Low