Findings

What do systematic reviews say?

2 questions · 3 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Imiquimod vs cidofovir

Complete response · women with usual‐type vulval intraepithelial neoplasia

Summary of findings for imiquimod showed no clear difference in response to treatment at 6 months ‐ complete response compared with cidofovir (moderate certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia 2016 · Cochrane Headline outcomes only
RR 1 [0.73, 1.37]
1 study · 180 participants
Moderate

Imiquimod vs placebo

Complete response · women with usual‐type vulval intraepithelial neoplasia

Summary of findings for imiquimod leads to higher response to treatment at 5 to 6 months ‐ complete response compared with placebo (high certainty).

2 findings from 1 review

Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia 2016 · Cochrane Headline outcomes only
RR 14.4 [2.97, 69.8]
3 studies · 104 participants
High
Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia 2016 · Cochrane Headline outcomes only
RR 18.24 [1.12, 296.41]
1 study · 47 participants
Moderate