Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Lung Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 1 · 33.3%

Response rate · combination with third‐generation drugs for advanced non‐small cell lung cancer

Carboplatin showed no clear difference in response rate compared with cisplatin chemotherapy (high certainty).

1 finding from 1 review

Objective response rate · non‐small cell lung cancer in the elderly population

Non‐platinum therapies probably leads to higher objective response rate (ORR) compared with platinum combination (moderate certainty).

1 finding from 1 review

Chemotherapy for advanced non‐small cell lung cancer in the elderly population 2015 · Cochrane Headline outcomes only
RR 1.57
11 studies · 1432 participants
Moderate

Objective response rate · non‐small cell lung cancer in the elderly population

Non‐platinum single‐agent may leads to higher objective response rate (ORR) compared with non‐platinum combination treatment (low certainty).

1 finding from 1 review

Chemotherapy for advanced non‐small cell lung cancer in the elderly population 2015 · Cochrane Headline outcomes only
RR 1.79
5 studies · 1014 participants
Low