Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Pain control and patient management

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No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
Use of rescue analgesia recorded in 7 studies; only 2 reported counts (Tuncer 2014: 2 participants; Bruno 2011: 6 participants); no class/dose/timing reported; not pooled. SoF cell: 'Not reported'.
7 studies
GRADE not reported

Ibuprofen taken pre-emptively (about 1 hour before treatment) vs Ibuprofen taken post-treatment

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Ibuprofen taken pre-emptively (about 1 hour before treatment) showed no clear difference in rescue analgesia compared with ibuprofen taken post-treatment; GRADE not reported.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
RR 0.8 [0.3, 1.9]
2 studies · 41 participants
GRADE not reported

NSAID (systemic) vs paracetamol

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

It is very uncertain whether NSAID (systemic) changes rescue analgesia compared with paracetamol (very low certainty).

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
RR 1.5 [0.6, 3.6]
1 study · 159 participants
Very low