Benzodiazepines (topical clonazepam) vs placebo
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether benzodiazepines (topical clonazepam) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
2 findings from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · topical clonazepamMD -1.89 [-2.19, -1.59]2 studies · 111 participantsVery low
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomeslong-term (>3 to 6 months) · topical clonazepamMD -1.39 [-1.96, -0.83]1 study · 66 participantsVery low