Findings

What do systematic reviews say?

2 questions · 3 findings · 1 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Rituximab vs placebo or control

Relapse at 3 months · SSNS in children

Rituximab probably leads to lower relapses at 3 months compared with placebo or control (moderate certainty).

1 finding from 1 review

Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children 2020 · Cochrane Headline outcomes only
RR 0.32 [0.14, 0.7]
3 studies · 132 participants
Moderate

Rituximab vs placebo or control

Relapse · SSNS in children

Rituximab probably leads to lower relapses at 6 months compared with placebo or control (moderate certainty).

2 findings from 1 review

Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children 2020 · Cochrane Headline outcomes only
RR 0.23 [0.12, 0.43]
5 studies · 269 participants
Moderate
Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children 2020 · Cochrane Headline outcomes only
RR 0.63 [0.42, 0.93]
3 studies · 198 participants
Moderate