Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Baclofen vs placebo

Relapse: return to any drinking at end of treatment · alcohol use disorder

Summary of findings table ‐ Baclofen probably leads to lower relapse: return to any drinking at end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Baclofen for alcohol use disorder 2023 · Cochrane Headline outcomes only
RR 0.87 [0.77, 0.99]
12 studies · 1057 participants
Moderate

Baclofen vs naltrexone

Relapse: return to any drinking at end of treatment · alcohol use disorder

It is very uncertain whether summary of findings table ‐ Baclofen changes relapse: return to any drinking at end of treatment compared with naltrexone (very low certainty).

1 finding from 1 review

Baclofen for alcohol use disorder 2023 · Cochrane Headline outcomes only
RR 2.5 [1.12, 5.56]
1 study · 60 participants
Very low

Baclofen vs acamprosate

Relapse: return to any drinking at end of treatment · alcohol use disorder

It is very uncertain whether summary of findings table ‐ Baclofen changes relapse: return to any drinking at end of treatment compared with acamprosate (very low certainty).

1 finding from 1 review

Baclofen for alcohol use disorder 2023 · Cochrane Headline outcomes only
RR 1.25 [0.71, 2.2]
1 study · 60 participants
Very low