Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

70 questions · 70 findings · 1 reviews

No studies found 44 · 62.9%GRADE not reported 0 · 0%Very low 7 · 10%Low 7 · 10%Moderate 4 · 5.7%High 8 · 11.4%

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 12 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 12 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 18 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 18 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 24 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 24 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review