Findings

What do systematic reviews say?

28 questions · 28 findings · 1 reviews

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No studies found 17 · 60.7%GRADE not reported 0 · 0%Very low 3 · 10.7%Low 4 · 14.3%Moderate 3 · 10.7%High 1 · 3.6%

Intermittent oral or rectal diazepam vs placebo or no treatment

Recurrent seizure at 60 months or greater · children with febrile seizures

It is very uncertain whether intermittent oral or rectal diazepam changes recurrent seizure at 60 months or greater compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 0.08 [0, 1.31]
1 study · 60 participants
Very low

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 6 months · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 12 months · children with febrile seizures

Continuous phenobarbital showed no clear difference in recurrent seizure at 12 months compared with intermittent rectal or oral diazepam (low certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 1.48 [0.75, 2.94]
1 study · 145 participants
Low

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 18 months · children with febrile seizures

It is very uncertain whether continuous phenobarbital changes recurrent seizure at 18 months compared with intermittent rectal or oral diazepam (very low certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 1.25 [0.36, 4.38]
1 study · 100 participants
Very low

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 24 months · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 36 months · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 48 months · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous phenobarbital vs intermittent rectal or oral diazepam

Recurrent seizure at 60 months or greater · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found