Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Oral factor Xa inhibitors vs conventional anticoagulation

Recurrent VTE · participants with diagnosed DVT

Oral factor Xa inhibitors showed no clear difference in recurrent VTE (3 to 12 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
OR 0.85 [0.71, 1.01]
13 studies · 17505 participants
Moderate

Oral direct thrombin inhibitors (DTIs) vs conventional anticoagulation

Recurrent VTE · participants with diagnosed DVT

Oral DTIs showed no clear difference in recurrent VTE (7 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
OR 1.17 [0.83, 1.65]
3 studies · 5994 participants
Moderate