Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Skin

No studies found 2 · 33.3%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Recurrence · participants with confirmed toenail onychomycosis

Azole showed no clear difference in recurrence rate compared with placebo (low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 0.55 [0.29, 1.07]
1 study · 26 participants
Low

Recurrence · participants with confirmed toenail onychomycosis

It is very uncertain whether griseofulvin changes recurrence rate compared with azole (very low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 4 [0.26, 61.76]
1 study · 7 participants
Very low

Recurrence · participants with confirmed toenail onychomycosis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Recurrence · participants with confirmed toenail onychomycosis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Recurrence · participants with confirmed toenail onychomycosis

Azole showed no clear difference in recurrence rate compared with terbinafine (low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 1.11 [0.68, 1.79]
5 studies · 282 participants
Low

Recurrence · participants with confirmed toenail onychomycosis

Terbinafine may leads to lower recurrence rate compared with placebo (low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 0.05 [0.01, 0.38]
1 study · 35 participants
Low