Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Oral Health

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No studies found 5 · 62.5%GRADE not reported 1 · 12.5%Very low 1 · 12.5%Low 0 · 0%Moderate 1 · 12.5%High 0 · 0%

Surgery plus radiotherapy vs Radiotherapy alone

Recurrence · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Recurrence: not reported.
0 studies
No studies found

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Recurrence · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Recurrence: not reported for the oral cancer subgroup (Iyer 2015).
0 studies
No studies found

Surgery plus radiotherapy vs Radiotherapy alone

Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Locoregional recurrence: not reported.
0 studies
No studies found

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Recurrence: outcome not reported in a usable way (Mehanna 2017: nodal recurrence 3 vs 1; distant metastases 21 vs 23).
1 study
GRADE not reported

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Locoregional recurrence: reported difference between groups not statistically significant (P=0.355), but no useable data; 32 participants (1 RCT, Iyer 2015).
1 study · 32 participants
Very low

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in locoregional recurrence compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
3 years
HR 1.00 [0.94, 1.06]
1 study · 564 participants
Moderate

Surgery vs Radiotherapy alone

Recurrence · Adults with oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Recurrence: not reported.
0 studies
No studies found

Surgery vs Radiotherapy alone

Locoregional recurrence · Adults with oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Locoregional recurrence: not reported.
0 studies
No studies found