Findings

What do systematic reviews say?

99 questions · 102 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 74 · 72.5%Very low 11 · 10.8%Low 13 · 12.7%Moderate 4 · 3.9%High 0 · 0%

Low-level laser therapy (LLLT) + calcium hydroxide vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.50 [0.15, 1.64]
1 study · 30 participants
GRADE not reported

Low‐level laser therapy vs Low-level laser therapy (LLLT) + calcium hydroxide

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with low-level laser therapy (LLLT) + calcium hydroxide; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.24, 4.18]
1 study · 30 participants
GRADE not reported

Diode laser + mineral trioxide aggregate (MTA) vs Formocresol (FC) + zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser + mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with formocresol (FC) + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
mean 15.7 months
RR 4.00 [0.48, 33.42]
1 study · 52 participants
GRADE not reported

Calcium hydroxide (CH) vs Portland cement (PC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 17.00 [1.07, 270.41]
1 study · 30 participants
GRADE not reported

Biodentine vs Propolis

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with propolis; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 0.43 [0.12, 1.47]
1 study · 50 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.83 [0.80, 4.19]
1 study · 50 participants
GRADE not reported

OrthoMTA vs RetroMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

OrthoMTA showed no clear difference in radiological failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.70 [0.12, 3.98]
1 study · 96 participants
GRADE not reported

Portland cement (PC) vs Portland cement + iodoform or Portland cement + zirconium oxide

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
up to 24 months
No events in any participant; not estimable
1 study · 30 participants
GRADE not reported

Mineral trioxide aggregate (MTA) vs Sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.33 [0.04, 2.99]
1 study · 50 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher radiological failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 42.63 [2.65, 685.54]
1 study · 109 participants
GRADE not reported

Low‐level laser therapy vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 0.50 [0.15, 1.64]
1 study · 30 participants
GRADE not reported

3Mix (ciprofloxacin + metronidazole + minocycline) vs 3Mixtatin

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
No radiological failure in any participant; not estimable
1 study · 160 participants
GRADE not reported

Electrosurgery vs Ferric sulphate (FS)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Electrosurgery showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 1.25 [0.38, 4.12]
2 studies · 50 participants
Low

Self-etch adhesive + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 3.00 [0.13, 69.52]
1 study · 40 participants
Very low

Mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) led to lower radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.10 [0.01, 0.72]
1 study · 50 participants
GRADE not reported

Diode laser vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 2.00 [0.75, 5.33]
1 study · 80 participants
GRADE not reported

Ferric sulphate (FS)/zinc oxide and eugenol (ZOE) pulpotomy vs Sedanol (ZOE) pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate (FS)/zinc oxide and eugenol (ZOE) pulpotomy showed no clear difference in radiological failure compared with sedanol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.60 [0.25, 1.46]
1 study · 291 participants
GRADE not reported

Erbium:YAG laser vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Erbium:YAG laser led to lower radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.31 [0.11, 0.90]
1 study · 91 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) may leads to higher radiological failure compared with zinc oxide and eugenol (ZOE) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 6.56 [2.58, 16.67]
4 studies · 161 participants
Low

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE) pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate/MTA pulpotomy showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
18 months
RR 0.84 [0.29, 2.39]
1 study · 172 participants
GRADE not reported