What do systematic reviews say?

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

The review found no eligible studies for this question.

• Flossing for the management of periodontal diseases and dental caries in adults 2011 · Cochrane All outcomes
  Not estimable (0 studies). See comment: No included study assessed quality of life as an outcome.
  0 studies
  No studies found

Interdental brushing plus toothbrushing vs Toothbrushing alone

The review found no eligible studies for this question.

• Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
  Not estimable. No included study assessed quality of life as an outcome. (See comment)
  0 studies
  No studies found

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

The review found no eligible studies for this question.

• Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
  Not estimable. No included study assessed quality of life as an outcome. (See comment)
  0 studies
  No studies found

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

• Guided tissue regeneration for periodontal infra-bony defects 2006 · Cochrane All outcomes
  Cortellini 2001: 36% of GTR patients reported the procedure interfered with daily activity for an average of 2.7 days versus 32% of controls for an average of 2.4 days; no significant difference for postoperative pain…
  1 study
  GRADE not reported