Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Hypoxia‐inducible factor (HIF) stabilisers vs erythropoiesis‐stimulating agent (ESA)

Proportion reaching target haemoglobin Median · people with CKD (including HD and PD)

Hypoxia‐inducible factor (HIF) stabilisers showed no clear difference in proportion reaching target haemoglobin Median compared with erythropoiesis‐stimulating agent (ESA) (low certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 1 [0.93, 1.07]
14 studies · 4601 participants
Low

Hypoxia‐inducible factor (HIF) stabilisers vs placebo

Proportion reaching target haemoglobin Median · people with CKD (including HD and PD)

Hypoxia‐inducible factor (HIF) stabilisers probably leads to higher proportion reaching target haemoglobin Median compared with placebo (moderate certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 8.36 [6.42, 10.89]
10 studies · 5102 participants
Moderate