Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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Hypoxia‐inducible factor (HIF) stabilisers vs erythropoiesis‐stimulating agent (ESA)

Blood transfusion · people with CKD (including HD and PD)

Hypoxia‐inducible factor (HIF) stabilisers showed no clear difference in proportion of patients requiring blood transfusion Median compared with erythropoiesis‐stimulating agent (ESA) (moderate certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 0.87 [0.76, 1]
11 studies · 10786 participants
Moderate

Hypoxia‐inducible factor (HIF) stabilisers vs placebo

Blood transfusion · people with CKD (including HD and PD)

Hypoxia‐inducible factor (HIF) stabilisers probably leads to lower proportion of patients requiring blood transfusion Median compared with placebo (moderate certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 0.51 [0.44, 0.6]
8 studies · 4329 participants
Moderate