Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Phenobarbital vs levetiracetam

Proportion of infants who develop epilepsy post‐discharge · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post‐discharge compared with levetiracetam (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Proportion of infants who develop epilepsy post‐discharge · neonates with clinically diagnosed seizures

Summary of findings table ‐ Maintenance ASM showed no clear difference in proportion of infants who develop epilepsy post‐discharge compared with no maintenance ASM after achieving seizure control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Phenobarbital + bumetanide vs phenobarbital

Proportion of infants who develop epilepsy post‐discharge · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital + bumetanide changes proportion of infants who develop epilepsy post‐discharge compared with phenobarbital alone (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Treatment of clinical and electrographic seizures vs treatment of clinical seizures alone

Proportion of infants who develop epilepsy post‐discharge · neonates

Summary of findings table ‐ Treatment of clinical and electrographic… showed no clear difference in proportion of infants who develop epilepsy post‐discharge compared with treatment of clinical seizures alone (low certainty).

1 finding from 1 review