What do systematic reviews say?

Phenobarbital vs levetiracetam

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post‐discharge compared with levetiracetam (very low certainty).

• Anti‐seizure medications for neonates with seizures 2023 · Cochrane Headline outcomes only
  RR 0.92 [0.48, 1.76]
  1 study · 45 participants
  Very low