What do systematic reviews say?

Phenobarbital vs levetiracetam

Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the maximal… compared with levetiracetam (moderate certainty).

• Anti‐seizure medications for neonates with seizures 2023 · Cochrane Headline outcomes only
  RR 2.83 [1.78, 4.5]
  1 study · 83 participants
  Moderate