Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Proportion achieving target serum urate · people with chronic gout

Allopurinol showed no clear difference in proportion achieving target serum urate compared with benzbromarone (moderate certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.79 [0.56, 1.11]
2 studies · 101 participants
Moderate

Proportion achieving target serum urate · people with chronic gout

Allopurinol probably leads to higher proportion achieving target serum urate compared with placebo (moderate certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 49.11 [3.15, 765.58]
1 study · 51 participants
Moderate

Proportion achieving target serum urate · people with chronic gout

Allopurinol 100‐300 mg daily may leads to lower proportion achieving target serum urate compared with febuxostat 80 mg daily (low certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.56 [0.48, 0.65]
4 studies · 2618 participants
Low