Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Gynaecology and Fertility

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No studies found 1 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 2 · 50%High 0 · 0%

GnRHa treatment vs placebo or no pretreatment

Preoperative bleeding · women with uterine fibroids

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.71 [0.3, 1.68]
1 study · 199 participants
Moderate

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.39 [0.14, 1.06]
1 study · 203 participants
Moderate

SPRM vs placebo

Preoperative bleeding: Change in menstrual blood loss from baseline to end of treatment · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low