Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 7 findings · 2 reviews · Orthodontics

No studies found 0 · 0%GRADE not reported 4 · 57.1%Very low 1 · 14.3%Low 0 · 0%Moderate 2 · 28.6%High 0 · 0%

Clear aligners (Invisalign / thermoformed aligners) vs Conventional orthodontic appliance treatment

Plaque · Orthodontic patients undergoing comprehensive treatment (late mixed or permanent dentition, no active caries)

In randomized trials, clear aligners probably reduce plaque accumulation versus fixed appliances, though the subgroup estimate is imprecise and its CI crosses no effect (SMD -1.79, 95% CI -3.63 to 0.04; moderate certainty).

6 findings from 1 review
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1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

Plaque index (PI) / oral hygiene · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes visible plaque index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).

1 finding from 1 review