Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Neonatal

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No studies found 2 · 66.7%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Pentoxifylline with antibiotics (any dose or duration) vs pentoxifylline with antibiotics and immunoglobulin M‐enriched intravenous immunoglobulin

Periventricular leukomalacia · neonates with sepsis

The review found no eligible studies for this question.

1 finding from 1 review

Pentoxifylline for treatment of sepsis and necrotising enterocolitis in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pentoxifylline with antibiotics (any dose or duration) vs immunoglobulin M‐enriched intravenous immunoglobulin with antibiotics

Periventricular leukomalacia · neonates with sepsis

The review found no eligible studies for this question.

1 finding from 1 review

Pentoxifylline for treatment of sepsis and necrotising enterocolitis in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pentoxifylline with antibiotics (any dose or duration) vs placebo or no intervention

Periventricular leukomalacia · neonates with sepsis

It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes periventricular leukomalacia compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Pentoxifylline for treatment of sepsis and necrotising enterocolitis in neonates 2023 · Cochrane Headline outcomes only
RR 0.5 [0.1, 2.63]
1 study · 120 participants
Very low